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World Community Grid

http://www.worldcommunitygrid.org/

Mission is to create the largest public computing grid benefiting humanity. Currently supporting the Human Proteome Folding project to provide scientists with data that predicts the shape of a very large number of human proteins.

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ZetaGrid

http://www.zetagrid.net/

An open source and platform independent grid system that uses idle CPU cycles from participating computers. ZetaGrid solves one problem in practice: numerical verification of the Riemann Hypothesis.

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